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Ultram is a centrally acting narcotic analgesic that should be used orally to treat moderate to severe pain in adults. Ultram (Tramadol) ER (extended release) is used to relieve pain and has a lengthy duration of action. It should not be taken on an as-needed basis to relieve pain. According to IMS and Information Technology Company, about 43 million tramadol prescriptions were issued in the United States in 2013.Tramadol was authorized as a non-controlled analgesic by the United States Food and Drug Administration (FDA) in 1995. Tramadol’s restricted substance classification has been changed many times since 1995 as a result of drug misuse and diversion. In 2011, the Drug Abuse Warning Network (DAWN) recorded 20,000 emergency department visits due to tramadol non-medical use. According to the National Survey on Drug Use and Health (NSDUH), 3.2 million individuals in the United States aged 12 and up took tramadol for non-medical reasons in 2012.
Tramadol is a restricted drug in 50 states throughout the United States:
The United States Drug Enforcement Administration (DEA) stated in 2014 that tramadol has been put on Schedule IV of the Controlled Substances Act (CSA), starting August 18, 2014. All Tramadol formulations have been subjected to the regulation. Tramadol was formerly a restricted drug. The rescheduling was made in response to increasing concerns about opioid analgesic overuse, abuse, and overdosing, as well as addiction.
Tramadol could only be renewed up to five times in a six-month period after the prescription was issued as of August 18, 2014. A fresh prescription would be needed after six months. The regulation applies to all schedule III and IV restricted substances.